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Drug Name Antabuse

Antabuse (Disulfiram)

Drug Uses Antabuse

Antabuse (Disulfiram) is used to help treat alcoholism.

Possible Side Effects Antabuse

This medication may cause headache, drowsiness, restlessness, skin rash, acne, garlic-like aftertaste, changes in vision. Inform your doctor if any of these effects persist or worsen. Unlikely to occur but report immediately: tingling hands or feet, fatigue, weakness, loss of appetite, nausea, vomiting, strong stomach pains, dark urine, yellowing of the eyes or skin. If you notice other effects not listed above, contact your doctor or pharmacist.

Drug Class and Mechanism Antabuse

Antabuse produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Antabuse blocks the oxidation of alcohol at the acetaldehyde stage. During alcohol metabolism after antabuse intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the same amount of alcohol alone. Accumulation of acetaldehyde in the blood produces a complex of highly unpleasant symptoms referred to as the antabuse-alcohol reaction. This reaction, which is proportional to the dosage of both antabuse and alcohol, will persist as long as alcohol is being metabolized. Antabuse does not appear to influence the rate of alcohol elimination from the body.

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Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions.If you will be taking this medicine for an extended period of time, be sure to obtain necessary refills before your supply runs out.

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